Advances in Biomembranes and Lipid Self-Assembly, Volume 23 by Ales Iglic, Chandrashekhar V. Kulkarni, Michael Rappolt

By Ales Iglic, Chandrashekhar V. Kulkarni, Michael Rappolt

The Elsevier publication sequence Advances in Biomembranes and Lipid Self-Assembly (previously titled Advances in Planar Lipid Bilayers and Liposomes), presents a world platform for a huge group of experimental and theoretical researchers learning mobilephone membranes, lipid version membranes, and lipid self-assemblies from the micro- to the nanoscale. Planar lipid bilayers are greatly studied as a result of their ubiquity in nature and locate their software within the formula of biomimetic version membranes and within the layout of man-made dispersion of liposomes.

Moreover, lipids self-assemble right into a wide variety of different constructions together with micelles and the liquid crystalline hexagonal and cubic levels. Consensus has been reached that curved membrane stages do play a big function in nature besides, specially in dynamic approaches akin to vesicles fusion and mobile communique. Self-assembled lipid buildings have huge, immense power as dynamic fabrics starting from synthetic lipid membranes to mobilephone membranes, from biosensing to managed drug supply, from pharmaceutical formulations to novel nutrients items to say a number of. An collection of chapters during this quantity represents either unique learn in addition to complete reports written by way of global major specialists and younger researchers.

  • Surveys contemporary theoretical and experimental effects on lipid micro- and nanostructures
  • Presents strength makes use of of purposes like clinically appropriate diagnostic and healing systems, biotechnology, pharmaceutical engineering, and nutrients products
  • Provides either unique study in addition to finished stories written via international top specialists and younger researchers
  • Provides an international platform for a wide neighborhood of experimental and theoretical researchers learning telephone membranes, lipid version membranes, and lipid self-assemblies from the micro- to the nanoscale.

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Extra resources for Advances in Biomembranes and Lipid Self-Assembly, Volume 23

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Beyond micrometers, it has been shown that nanometric (1–500 nm) features can elicit specific cell response [65,66]. In addition, it is known that the recognition of morphology by cells also depends on cell type and origin [67]. Surface morphology is also important in protein adsorption and subsequent cell response. Thus, Riedel and colleagues showed that adsorption of albumin dramatically increased due to presence of nanoislands [68]. While Vertegel et al. showed that the adsorption of lysozyme to silica nanoparticles decreased with decreasing nanoparticle size [69].

Donovan and Zimmerman [87] attributed longer clotting time (lower thrombogenicity) of polyethylene to low surface wettability. Vogler et al. [88] showed that coagulation is the step function of surface wettability, with very low activation for poorly wettable surfaces and high activation for fully wettable surfaces. Contrary to this, it was shown by Sperling et al. [55] that surfaces with more hydrophobic characteristics (contact angle 72–112°) greatly enhance platelet adhesion. , where the most hydrophobic surfaces showed the highest number of adherent platelets in a highly activated state.

As can be seen from Table 1, the concentration of oxygen functional groups increased and it seems that the surface became saturated with oxygen already after 30 s of treatment. While for the case of nitrogen plasma treatment, the incorporation of nitrogen as well as oxygen functional groups was observed. However, for this case, surface saturation with newly formed functional groups was achieved already after 3 s of treatment. Type of functional groups on oxygen plasma-treated surface from high-resolution C1s spectra was studied in more detail, as oxygen plasma-treated surfaces highly influenced platelet adhesion.

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