Early Nutrition: Impact on Short- and Long-Term Health by H. van Goudoever, S. Guandalini, R.E. Kleinman

By H. van Goudoever, S. Guandalini, R.E. Kleinman

During this publication, a specific team of foreign specialists evaluation dietary practices and feeding behaviors in infancy and early early life. They current the newest wisdom on feeding practices throughout the interval thought of and their influence on development, improvement, and fast and long term healthiness. one of many major subject matters mentioned consists of feeding practices within the infant severe care unit, focusing on using human donor milk and probiotics within the vitamin of untimely and ailing newborns. one other aspect of concentration is the factors and the impression of an inadequate consumption of chosen micronutrients, equivalent to iron and zinc, that's hugely everyday really within the constructing global. along with, this ebook comprises details at the impression of early feeding conduct at the later improvement of a couple of health-related concerns reminiscent of foodstuff asthma, later foodstuff personal tastes and consuming conduct, weight problems, bone improvement, the chance of constructing celiac disorder in genetically predisposed childrens. This quantity presents crucial studying for pediatricians, scientific investigators and medical examiners attracted to the consequences of early foodstuff on well-being.

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Additional resources for Early Nutrition: Impact on Short- and Long-Term Health (Nestle Nutrition Workshop Series: Pediatric Program)

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The second question is: is there any literature to support that omega-3 and omega-6 intakes in early infancy affect the manifestation of heart disease later on in life? Dr. Innis: Following the argument related to the metabolic and biochemical physiology of humans, we know that dietary intakes of n-6 linoleic acid were low, and likely less than 3% of energy, until about 150 years ago. We also know that the amount of linoleic acid needed to saturate the Δ6 desaturase is very low, probably 1–2% of dietary energy.

27 McCurdy CE, Bishop JM, Williams SM, et al: Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates. J Clin Invest 2009;119:323–35. 28 Novak EM, Lee EK, Innis SM, et al: Identification of novel protein targets regulated by maternal dietary fatty acid composition in neonatal rat liver. Proteomics 2009;73:41–49. 29 Massiera F, Barbry P, Guesnet P, et al: A Western-like fat diet is sufficient to induce a gradual enhancement in fat mass over generations. J Lipid Res 2010;51:2352–2361.

27 Novak/Keller/Innis Dr. Gottrand: You nicely showed us that low omega-3 intake in the mother has an impact on the brain and on the liver. Are you aware of any work published on the gut in such models? Dr. Innis: Yes. Studies from our laboratory have shown that the early fatty acid supply impacts intestinal development and susceptibility to later inflammatory responses [1, 2]. Dr. van Goudoever: Since DHA has such an effect on brain development and there is a wide variation in DHA in breast milk among different populations around the world, does that affect brain development around the world?

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