Membrane Proteins by Douglas C. Rees (Eds.)

By Douglas C. Rees (Eds.)

This quantity covers 2 significant themes: Foundations and Membrane Protein buildings. Key good points * Foundations * Bioenergetic approaches * Channels and Receptors

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Chem. 276, 32399–32402. , Glick, B. , and Kronidou, N. (1996). Translocation arrest of an intramitochondrial sorting signal next to TIM11 at the inner-membrane import site. Nature 384, 585–589. Tusnady, G. , and Simon, I. (1998). Principles governing amino acid composition of integral membrane proteins: application to topology prediction. J. Mol. Biol. 283, 489–506. Urbanus, M. , Scotti, P. , de Gier, J. W. , Samuelson, J. , Dalbey, R. , and Luirink, J. (2001). Sec-dependent membrane protein insertion: sequential interaction of nascent FtsQ with SecY and YidC.

A. Lipid Interactions with Transmembrane Proteins . . . . . . . . . . . B. van der Waals Interactions . . . . . . . . . . . . . . . . . . . . C. Hydrogen Bonding . . . . . . . . . . . . . . . . . . . . . . . D. Salt Bridges . . . . . . . . . . . . . . . . . . . . . . . . . . . VI. Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . References . . . .

7 μm latex beads at an air/water interface, and would be expected to operate on membrane proteins (Kralchevsky, 1997). Basically, the lateral force originates from the deformation of the bilayer in the presence of a protein with a hydrophobic region of different thickness than the bilayer. An example in which the hydrophobic region of the protein is too long for the bilayer tails is illustrated in Fig. 6. ) CONSTRUCTION OF HELIX-BUNDLE MEMBRANE PROTEINS 33 FIG. 6. Lateral capillary forces can assist protein–protein associations.

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