By Jerome Wilson (auth.), Lovell A. Jones Ph.D. (eds.)
Minorities and Cancer greatly surveys the matter of melanoma in minority groups. major epidemiologists talk about melanoma prevalence and mortality in minority populations, together with black americans, Hispanics, American Indians, and Asian americans. significant sections evaluate melanoma prevention and detection courses on hand to the personal perform medical professional and the neighborhood, learn findings on melanoma in minority teams, and melanoma remedy. the ultimate chapters summarize the matter and its attainable recommendations as perceived via leaders on the American melanoma Society, the nationwide melanoma Institute, the place of work of Minority well-being Affairs of the dep. of wellbeing and fitness and Human providers, and Meharry clinical collage, a number one minority clinical college within the United States.
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Pathology slides from selected sites should be obtained for systemic review. These studies would provide accurate data on the specific histologic types of cancer, and it is likely that different histologic types will provide additional insight on rate differences between Blacks and Whites. Case-Control Studies Descriptive studies have adequately documented differences in incidence rates of several cancers in Blacks and Whites. Case-control studies designed to explain these observed differences should be conducted.
Stomach Cancer Although the incidence of stomach cancer has been declining since 1930 in the United States, the rate of this malignancy is still comparatively high among Japanese and Hawaiians of both genders, Hawaiians having particularly elevated rates. Evidence suggests that diet is an important determinant of stomach cancer development (Howson et al. 1986). A positive association with the disease has been found for rice and carbohydrate (Segi et al. 1957; Modan et al. 1974). Experimental studies have pointed to a role ofN-nitroso compounds in the etiology of stomach cancer (Sugimura and Kawachi 1978; Maekawa et al.
The technology for sophisticated biomarker analysis in the case-control design is available. The next logical step is to pursue aggressively those laboratory assays in which suggested associations have been observed or have a sound biologic basis. Since Black persons represent a high-risk group for a number of cancers, studies of normal individuals in the highest risk group of Blacks may be useful. A large proportion of members of such a group is destined to develop the cancer in question. A comparison of Blacks and Whites should take into account socioeconomic or occupational differences or both if the cancer under investigation is known to be related to these variables.