Mitochondria and Cancer by Kjerstin M. Owens, J. S. Modica-Napolitano, Keshav K. Singh

By Kjerstin M. Owens, J. S. Modica-Napolitano, Keshav K. Singh (auth.), Leslie Costello, Keshav Singh (eds.)

Nearly a century of medical learn has printed that mitochondrial disorder is likely one of the most typical and constant phenotypes of melanoma cells. a few awesome adjustments within the mitochondria of standard and melanoma cells were defined. those comprise transformations in mitochondrial metabolic job, molecular composition of mitochondria and mtDNA series, in addition to in alteration of nuclear genes encoding mitochondrial proteins. This ebook, Mitochondria and Cancer, edited by means of Keshav okay. Singh and Leslie C. Costello, provides thorough analyses of mitochondrial disorder as one of many hallmarks of melanoma, discusses the scientific implications of mitochondrial defects in melanoma, and as special mobile goals for novel and selective anti-cancer therapy.

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