Neurology of the Infant by Francesco Guzzetta

By Francesco Guzzetta

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Dehaene, S. (2006): Functional organization of perisylvian activation during presentation of sentences in preverbal infants. Proc. Natl. Acad. Sci. USA 103, 14240–14245. , Dubowitz, V. M. (1987): Neurological, electrophysiological and MRI abnormalities in infants with extensive cystic leukomalacia. Neuropediatrics 18, 61–66. S. & Hellstrom-Westas, L. (2005): Role of cerebral function monitoring in the newborn. Arch. Dis. Child. Fetal Neonatal Ed. 90, F201–F207. Dreyfus-Brisac, C. (1972): The electroencephalogram of fullterm newborns and premature infants.

1995): Predictive value of early neuroimaging, pulsed Doppler and neurophysiology in full term infants with hypoxic-ischaemic encephalopathy. Arch. Dis. Child. Fetal Neonatal Ed. 73, F75–F80. , Reits, D. & Spekreijse, H. (1996): Early predictors of cerebral visual impairment in infants with cystic leukomalacia. Neuropediatrics 27, 16–25. , Ori, L. & Frigieri, G. (1992): Bioelectric brain maturation in fullterm infants and in healthy and pathological preterm infants at term post-menstrual age. Early Hum.

The first deflection elicited during development is visible in preterm neonates at around 24 weeks’ gestational age (GA), and consists of a large negative wave occurring at approximately 300 ms (N300) (Fig. 8). , 1995). The second visible component emerges at around 34 weeks GA, consisting of a positive peak occurring at about 200 ms (P200). At term the response consists of a negativepositive-negative complex which will gradually achieve adult characteristics during the first 6 months of life, with a progressive decrease of the three main peak latencies.

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