Nutrition, Diet and Cancer by Sharmila Shankar, Rakesh K. Srivastava

By Sharmila Shankar, Rakesh K. Srivastava

Chemoprevention of melanoma has been the focal point of extensive study for greater than 20 years. Epidemiological proof has proven a small, yet major organization among fruit and vegetable consumption and a discount in melanoma danger. vitamin might account for approximately thirty 5 percentage of melanoma. huge claims were made for the effectiveness of specific diets in choosing one's hazard of constructing melanoma, starting from safeguard opposed to melanoma initiation, development and metastasis. a wide range of nutritional elements has been validated to be as potent in scuffling with off melanoma. in the direction of an elevated figuring out of the foodstuff, excercise and vitamin in combating melanoma or inhibiting its development has resulted in the invention and improvement of novel and potent medicines that keep watch over intracellular signaling community within the physique. this data should be very priceless to discover novel and powerful chemopreventive suggestions for lowering the future health burden of cancer.

Hippocrates, who proclaimed 25 centuries in the past, 'Let meals be thy drugs and medication be thy food'. They expected that one 3rd of all melanoma situations may be avoided by means of a more fit vitamin; statements that are broadly permitted within the medical literature. This publication covers the present state-of-the artwork wisdom at the effect of foodstuff and vitamin with nutrigenetics, dietary epigenomics, dietary transcriptomics, proteomics, and metabolomics procedure in melanoma prevention and remedy.

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R. Vidya Priyadarsini is gratefully acknowledged. References Akagi K, Hirose M, Hoshiya T, Mizoguchi Y et al (1995) Modulatory effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogenesis model. Cancer Lett 94(1):113–121 Akiyama T (2000) Wnt/“-catenin signaling. Cytokine Growth Factor Rev 11(4):273–282 Amin AR, Kucuk O, Khuri FR, Shin DM (2009) Perspectives for cancer prevention with natural compounds. J Clin Oncol 27(16):2712–2725 Androutsopoulos VP, Papakyriakou A, Vourloumis D, Spandidos DA (2011) Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.

Role of Spices in Inflammation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Role of Spices in Tumor Cell Survival . . . . . . . . . . . . . . . . . . . . . . . . . . . Role of Spices in Tumor Cell Proliferation. . . . . . . . . . . . . . . . . . . . . . . . . Role of Spices in Tumor Cell Metastasis and Angiogenesis . . . . . . . . . . . . . . . . Anticancer Effects of Spices in Combination .

Traditional Uses of Spices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Spices Against Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Role of Spices in Inflammation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Role of Spices in Tumor Cell Survival . . . . . . . . .

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